Simultaneous scintigraphic depiction of aldosteronoma and adrenal infarction.
نویسندگان
چکیده
Primary aldosteronism is a potentially curable cause of hypertension, especially when caused by an adrenal adenoma. Aldosteronomas because of their small size often elude techniques to locate them. This case illustrates the advantages, disadvantages and complications of noninvasive techniques used for their diagnosis. A patient with hypertension and hypokalemia underwent an adrenal venous effluent sampling for measurement of aldosterone concentrations. This procedure was complicated by an injury to the right adrenal gland. Subsequently, it was difficult to control the patient's hypertension and hypokalemia with medical therapy alone. A re-assessment years after his initial diagnosis included a CT scan, which now visualized a left adrenal tumor. The functional status of this tumor and lack of function of the previously injured right adrenal gland were demonstrated by NP-59 scintigraphy. This information modified the surgical intervention (adenectomy rather than total adrenalectomy) and the residual left sided adrenal tissue prevented adrenocortical insufficiency. A year later the patient remains euadrenal.
منابع مشابه
گزارش یک مورد هیپرآلدوسترونیسم به علت Aldosteronoma
Primary hyperaldosteronism is one of the few causes of hypertension that can be cured by surgery. Primary hyperaldosteronism is caused by adrenocortical adenoma or hyperplasia. It is important to differentiate between adrenal adenoma and hyperplasia because the preferred treatments are different. In all patients with new-onest or worsening hypertension the primary hyperaldosteronism should be c...
متن کاملPrimary hyperaldosteronism and adrenal incidentaloma: an argument for physiologic testing before adrenalectomy.
OBJECTIVE To determine the frequency of nonfunctioning adrenal masses in patients with primary hyperaldosteronism. DESIGN A case series. SETTING A tertiary care hypertension clinic. PATIENTS Twenty-seven consecutive patients with primary hyperaldosteronism. MEASUREMENTS Blood pressure, serum electrolytes, supine and upright plasma renin, cortisol and aldosterone levels, selective adrena...
متن کاملRegulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldosteronoma.
CONTEXT Primary adrenal Cushing's syndrome can result from the aberrant adrenal expression of several hormone receptors; this mechanism has not been explored in detail in aldosterone-producing tumors. OBJECTIVE The objective of the study was to evaluate a 56-yr-old male patient with an aldosteronoma for the regulation of aldosterone secretion by aberrant hormone receptors. RESULTS Renin-ind...
متن کاملTransarterial embolization of a hyperfunctioning aldosteronoma in a patient with bilateral adrenal nodules
Primary hyperaldosteronism often results in resistant hypertension and hypokalemia, which may lead to cardiovascular and cerebrovascular complications. Although surgery is first line treatment for unilateral functioning aldosteronomas, minimally invasive therapies may be first line for certain patients such as those who cannot tolerate surgery. We present a case of transarterial embolization (T...
متن کاملSpironolactone inclusions in an aldosteronoma.
Cain, Delver R., Van De Velde, Robert, and Shapiro, Stephen J.: Spironolactone inclusions in an aldosteronoma. Am. J. Clin. Pathol. 61: 412-416, 1974. Spironolactone cytoplasmic inclusions were found in an aldosteronoma but not in the adjacent zona glomerulosa of an adrenal gland that was removed because of aldosteronism. Their light and electron microscopic appearance was similar to that of pr...
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ورودعنوان ژورنال:
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine
دوره 37 5 شماره
صفحات -
تاریخ انتشار 1996